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10.1161/01.RES.0000020401.61826.EA

Biomarkers including HbA1c, fasting insulin, lipid profiles, and body composition measurements provide the quantitative feedback needed to determine whether the combined approach is producing the intended metabolic effects, whether adjustments to formulation or dosing are needed, and whether the balance between the two therapies remains appropriate as a woman's physiology evolves through and beyond the menopausal transition

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Reducing calorie content in the diet subsequently causes a decrease in protein consumption, which is an extremely important dietary component to maintain proper health of the skin since proteins make up more than 80% of the dry weight of the skin

10.1212/WNL.0b013e31827dec42 Neurology 13 BeningtonJ